Ulticept is manufactured by Concept Biosciences.
Ulticept comprises Ciprofloxacin as an active chemical compound. It is a synthetic antibiotic that has a wide spectrum activity against both gram-positive and gram-negative bacteria and belongs to a 2nd generation Fluoroquinolones.
– respiratory tract infections (RTIs) (acute and chronic bronchitis, obstructive airways disease (COPD), empyema, lung abscess, bronchiectasis, lobar and bronchopneumonia, acute exacerbation of cystic fibrosis, otitis media, sinusitis and mastoiditis);
– urinary tract infections (UTIs) (acute and chronic pyelonephritis, cystitis, urethritis, prostatitis, epididymitis and chronic complicated or recurrent UTI caused by multi-drug resistant organisms and/or Pseudomonas aeruginosa);
– skin and soft tissue infections (SSTIs) (infected ulcers, wound infections, abscesses, cellulitis, erysipelas, infected burns);
– surgical infections (peritonitis, intra-abdominal abscess, cholangitis, cholecystitis, empyema of gall bladder);
– bone and joint infections (acute and chronic osteomyelitis, septic arthritis);
– pelvic infections (Salpingitis, endometritis, pelvic inflammatory disease);
– sexually transmitted diseases (STDs) (Gonorrhoea);
– gastrointestinal infections (enteric fever, infective diarrhea);
– severe systemic infections (Septicaemia, bacteremia, infections in immunocompromised patients).
Ulticept® may induce tendinitis or tendon rupture in individuals of all age groups. Patients over 60 years of age, patients taking corticosteroids, patients with kidney, heart or lung transplants, with diabetes mellitus, musculoskeletal disorders are at a high risk.
MOA (mechanism of action):
Ciprofloxacin with its powerful bactericidal properties inhibits the action of enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are vital for bacterial DNA replication, transcription, repair, and recombination. The mechanism of action of Ciprofloxacin is different from that of penicillins, cephalosporins, aminoglycosides, macrolides, and tetracyclines, meaning that bacteria resistant to these classes of antibiotics may be susceptible to Ciprofloxacin.
Ciprofloxacin is effective against E. coli, Klebsiella pneumoniae, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Providencia rettgeri, Morganella morganii, Citrobacter diversus, Citrobacter freundii, Pseudomonas aeruginosa, Staphylococcus epidermidis and Streptococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, Campylobacter jejuni, Shigella flexneri and Shigella sonnei.
Ulticept pills should be swallowed whole and taken with a full glass of water.
Do not stop taking Ulticept suddenly.
The usual dose for most infections is 500 mg twice daily during 7-14 days.
For infections of the respiratory tract: 500 mg twice daily to 750 mg twice daily (7-14 days).
For malignant external otitis: 750 mg twice daily (28 days up to 3 months).
For infectious diarrhea: 500 mg twice daily (3-7 days).
For urinary tract infections:
acute uncomplicated cystitis – 250 mg twice daily;
mild to moderate – 250 mg twice daily;
severe or complicated – 500 mg twice daily.
Treatment is required for 3-10 days.
For skin and soft tissue infections:
mild to moderate – 500 mg twice daily;
severe or complicated – 750 mg twice daily (7-14 days).
For bone and joint infections:
mild to moderate 500 mg twice daily;
severe or complicated-750 mg twice daily.
Treatment may be required for 4-6 weeks or longer.
Gonorrhoea: 250 mg as single dose.
For pelvic infections:
Epididymo-orchitis and pelvic inflammatory disease: 500 mg twice daily to 750 mg twice daily (14 days).
Elderly patients should receive a lower dose.
Patients with reduced renal function, the half-life of Ciprofloxacin is prolonged and the dosage needs to be adjusted.
Missing a dose
If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Ulticept to compensate the missed dose.
If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.